Members Introduction

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  Professor

  Nobuaki Takahashi

  Education

  Mar 2006	B.Sc. Industrial Chemistry, Kyoto University
  Mar 2008	M.Sc. Department of Synthetic Chemistry and Biological Chemistry, Kyoto University
  November 2010	Ph.D. Department of Synthetic Chemistry and Biological Chemistry, Kyoto University

  Experience

  December 2010	Research Assistant Professor Advanced Biomedical Engineering Research Unit, Kyoto University Mentor: Prof. Yasuo Mori
  June 2014	Postdoctoral Fellow Department of Cell Biology, Harvard Medical School Supervisor: Prof. Joan S. Brugge
  June 2015	Instructor (Faculty) Department of Cell Biology, Harvard Medical School Mentor: Prof. Joan S. Brugge
  April 2019	Associate Professor The Hakubi Center for Advanced Research, Kyoto University
  January 2023	Associate Professor Department of Synthetic Chemistry and Biological Chemistry, Kyoto University
  December 2025	Professor Department of Synthetic Chemistry and Biological Chemistry, Kyoto University

  Awards

  August 2011	“Hot Topic” Research, Society for Neuroscience
  September 2011	Koichi Suzuki Memorial Award, The Japanese Biochemical Society
  December 2012	Koichi Suzuki Memorial Award, The Japanese Biochemical Society
  March 2013	Kiiichi Sagawa Award, The Physiological Society of Japan
  February 2014	Inoue Research Award for Young Scientists, Inoue Science Foundation
  April 2020	The Young Scientists’ Prize, Minister of Education, Culture, Sports, Science and Technology Award, Japanese Government
  April 2025	SPIRIT2 Award, Kyoto University
  December 2025	The JSPS Prize, JSPS

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  Assistant Professor

  Yoshifumi Ueda

  Education

  March 2011	B.Sc. Industrial Chemistry, Kyoto University
  March 2013	M.Sc. Department of Synthetic Chemistry and Biological Chemistry, Kyoto University
  March 2017	Completed coursework for Ph.D. in Department of Synthetic Chemistry and Biological Chemistry, Kyoto University without degree
  May 2025	Ph.D. Department of Synthetic Chemistry and Biological Chemistry, Kyoto University

  Experience

  April 2017	Researcher Department of Synthetic Chemistry and Biological Chemistry, Kyoto University
  January 2026	Assistant Professor Department of Synthetic Chemistry and Biological Chemistry, Kyoto University

  Achievements (Original)

  1. Ueda Y, Kiyonaka S, Selfors LM, Inoue K, Harada H, Doura T, Onuma K, Uchiyama M, Kurogi R, Yamada Y, Sun JH, Sakaguchi R, Tado Y, Omatsu H, Suzuki H, Aoun M, Nakayama T, Kajimoto T, Yano T, Holmdahl R, Hamachi I, Inoue M, Mori Y, and Takahashi N. “Intratumour oxidative hotspots provide a niche for cancer cell dissemination.”
  Nature Cell Biol 27, 530–543 (2025).

  2. Sakaguchi R, Takahashi N, Yoshida T, Ogawa N, Ueda Y, Hamano S, Yamaguchi K, Sawamura S, Yamamoto S, Hara Y, Kawamoto T, Suzuki R, Nakao A, Mori MX, Furukawa T, Shimizu S, Inoue R, and Mori Y. “Dynamic remodeling of TRPC5 channel-caveolin-1-eNOS protein assembly potentiates the positive feedback interaction between Ca²+ and NO signals.”
  J Biol Chem 300, 107705 (2025).

  3. Kohashi H, Nagata R, Tamenori Y, Amatani T, Ueda Y, Mori Y, Kasahara Y, Obika S, and Shimojo M. “A novel transient receptor potential C3/C6 selective activator induces the cellular uptake of antisense oligonucleotides.”
  Nucleic Acids Res. 52(9), 4784-4798 (2024).

  4. Miki K, Oe M, Suzuki K, Miki K, Mu H, Kato Y, Iwatake M, Yukawa H, Baba Y, Ueda Y, Mori Y, and Ohe K. “Dual-responsive near-infrared turn-on fluorescent probe for cancer stem cell-specific visualization.”
  J. Mater. Chem. B 12(28), 6959-6967 (2024).

  5. Oe M, Miki K, Ueda Y, Mori Y, Okamoto A, Funakoshi Y, Minami H, and Ohe K. “Deep-Red/Near-Infrared Turn-On Fluorescence Probes for Aldehyde Dehydrogenase 1A1 in Cancer Stem Cells.”
  ACS Sens. 6, 3320-3329 (2021)

  6. Takada Y, Hirano M, Kiyonaka S, Ueda Y, Yamaguchi K, Nakahara K, Mori MX, and Mori Y. “Rab3 interacting molecule 3 mutations associated with autism alter regulation of voltage-dependent Ca²+ channels.”
  Cell Calcium 58(3), 296-306 (2015)

  7. Takahashi N, Hamada-Nakahara S, Itoh Y, Takemura K, Shimada A, Ueda Y, Kitamata M, Matsuoka R, Hanawa-Suetsugu K, Senju Y, Mori MX, Kiyonaka S, Kohda D, Kitao A, Mori Y, and Suetsugu S. “TRPV4 channel activity is modulated by direct interaction of the ankyrin domain to PI(4,5)P2.”
  Nature Commun 5, 4994 (2014).

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  Researcher

  Sun Jiacheng

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  Assistant Research Staff

  Yuki Sakai

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  Ph.D. student

  Zhu Hong

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  Ph.D. student

  Yuki Tado

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  Master's Student

  Haruki Omatsu

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  Master's Student

  Kenya Jodai

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  Master's Student

  Satoshi Hirabayashi

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  Master's Student

  Wataru Nakata

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  Undergraduate Student

  Mizuto Imanishi

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  Undergraduate Student

  Hikaru Shima